Early testosterone gel for people on breathing machines
Part of Hormones & metabolism clinical trials.
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older
- Be expected to need an ICU breathing machine (invasive mechanical ventilation) for more than 48 hours
- If you can get pregnant: have a negative pregnancy test and use very effective birth control during treatment and for 7 months after the last dose
- If you are male and have a partner who can get pregnant: you/your partner must use effective birth control during treatment and for 4 months after the last dose
- Agree to consent through you or a legal representative (if you can’t consent yourself)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a combination of early exercises and treatments to help people in the ICU who are on a breathing machine for a long time. It aims to improve recovery and reduce complications.
This study tests a new way to check if your breathing muscles are strong enough to safely remove the breathing tube. It uses a special patch to measure how well your diaphragm works, which may help doctors make better decisions about when to take the tube out.
This trial tests if testosterone supplements can improve quality of life for men with low testosterone who are no longer receiving active cancer treatment. It aims to help with symptoms like fatigue and low mood.
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
This Phase 2 study tests how well a testosterone skin treatment (testosterone delivered through the skin) works in healthy adults. It also checks how your body absorbs and handles the medicine, using repeated blood draws and on-site visits.
This Phase 2 trial tests different doses of a testosterone skin patch to see which works best and is absorbed safely. It may help men with low morning testosterone who can meet study requirements like non-smoking and multiple blood draws.
Hear when a new Critical Illness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.