Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT07822243Recruiting
Antibiotic penetration in critically ill children
This study looks at why some antibiotics given through a vein may reach infections differently in very sick children. It aims to make sure medicines are given in the best way to help children in the intensive care unit recover.
GhentAges 1 month–15 years - NCT07761364Recruiting
Contact with family in the intensive care unit
This study looks at how a visit from your main family caregiver affects your body while you are in the intensive care unit (ICU). It aims to see if having that personal contact can help you feel better and recover.
Mexico City, Mexico CityAges 18–59 - NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT07585500Recruiting
Virtual Reality to Help Recovery in ICU Patients
This study tests whether using virtual reality (VR) glasses can help patients recover better after spending time in the intensive care unit. The VR program is designed to help regain strength, movement, and mental function during recovery.
Porto, Porto DistrictAges 18 years+ - NCT07510776Recruiting
Understanding long-term critical illness
This study looks closely at patients who stay in the ICU for 5 days or more to understand why some people recover more slowly. It may help doctors find better ways to support you during and after a long ICU stay.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07478367Recruiting
Muscle weakness in hospitalized patients outside the ICU
This study looks at muscle weakness that can develop when you are in the hospital for an acute illness but not in the intensive care unit (ICU). It aims to understand how common this weakness is and what factors might be involved.
RozzanoAges Any age - NCT07420946Recruiting
Expert opinions on a lung clearance device for ICU patients
This study gathers expert opinions from healthcare professionals about using a device called MI-E to help clear airways in critically ill patients. If you are a clinician with experience in this area, your input could help shape future guidelines.
NaplesAges Any age - NCT07390773Recruiting
Supporting decisions for critically ill children
This study tests a program called BRIDGE that helps parents, doctors, and nurses talk about difficult medical decisions for seriously ill children. It focuses on improving communication and understanding between families and the care team.
San Francisco, CaliforniaAges Any age - NCT07345169Recruiting
Immune and inflammation study in ICU patients
This study looks at how your immune system and inflammation affect your recovery in the intensive care unit. Researchers want to understand why some patients do better than others.
ParisAges 18 years+ - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT07076524Recruiting
Muscle wasting and swallowing in critically ill patients
This study looks at muscle loss and swallowing problems in very ill patients on breathing machines in the intensive care unit. It aims to understand these issues better, which could help improve care for future patients.
LondonAges 18 years+ - NCT06727903Recruiting
Predicting survival for older ICU patients
This study aims to create a tool to predict survival in older adults (75+) who are admitted to the ICU from the emergency room. It may help doctors better understand individual risks and make more informed care decisions.
Badalona, BarcelonaAges 75 years+ - NCT06006000Recruiting
Supporting recovery after ICU stay for older adults
This study looks at the needs of older adults (65+) after a serious ICU stay. The goal is to help people recover better at home with support from a family or friend caregiver.
New Haven, ConnecticutAges 65 years+ - NCT03810768Recruiting
Metabolomics study of ICU-acquired weakness after surgery
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
Vienna, State of ViennaAges 18 years+ - NCT06576895Recruiting
Nutrition study in critically ill adults
This study looks at how nutrition is given to adults in the intensive care unit (ICU). It aims to understand current practices and may help improve care for future patients.
Melbourne, VictoriaAges 18 years+ - NCT07521111Recruiting
Stomach Blood Flow and Feeding Tolerance in Critical Illness
This study examines whether measuring blood flow in the stomach using ultrasound can predict which hospitalized patients will struggle to tolerate tube feeding. Researchers hope this simple test might help doctors adjust feeding plans earlier and improve patient outcomes.
ShanghaiAges 18 years+ - NCT07401420Recruiting
Study on life-sustaining treatments in critically ill children
This study asks experienced critical care doctors about decisions they make when providing life-sustaining treatments to critically ill children, especially around end-of-life care. Your insights could help improve how these difficult situations are handled.
GothenburgAges 18 years+ - NCT07372586Recruiting
Behavioral health support after ICU stay
This study tests a collaborative care model for mental health and recovery after an ICU stay. You might qualify if you visit the MUSC ICU Recovery Clinic within six months of leaving the hospital.
Charleston, South CarolinaAges 18 years+ - NCT06786390Recruiting
Walking recovery after muscle weakness
This trial tests if a walking program combined with electrical stimulation can help people recover walking ability after critical illness. It is for patients who developed limb weakness in the hospital and were independent before their illness.
MilanAges 18–85 - NCT07301970Recruiting
Remifentanil dosing in low-weight ICU patients
This study looks at how the sedative remifentanil works in critically ill patients who are underweight or normal weight. It aims to find the right dose for these patients while they are on a breathing machine in the ICU.
ShanghaiAges Any age - NCT07178626Recruiting
Biomarkers and feeding tolerance in ICU patients
This study looks at whether certain biomarkers and stomach motility measurements can help predict feeding intolerance in critically ill patients who cannot eat by mouth. It aims to improve how patients are fed in the ICU.
ChangchunAges 18 years+ - NCT07173504Recruiting
Continuous vs. intermittent tube feeding in ICU patients
This trial compares giving tube feeding continuously versus taking breaks to see which approach helps critically ill patients' metabolism better. It is for adults in the ICU who need a breathing tube and will be fed through a stomach tube.
Ede, GelderlandAges 18 years+ - NCT07173855RecruitingPhase 4
Magnesium replacement in ICU patients
This trial tests whether giving magnesium as part of a standard hospital protocol can lower the risk of irregular heartbeat and improve survival in patients admitted to the intensive care unit.
Ajax, OntarioAges 16 years+
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Critical Illness trials by city
Studies with a site in or near these metro areas.
Critical Illness trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 334 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.