Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 355 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT07761364Recruiting
Contact with family in the intensive care unit
This study looks at how a visit from your main family caregiver affects your body while you are in the intensive care unit (ICU). It aims to see if having that personal contact can help you feel better and recover.
Mexico City, Mexico CityAges 18–59 - NCT03529617Recruiting
Study of how a liposomal antifungal behaves in sick patients
This trial studies how liposomal amphotericin B (a drug used to treat serious fungal infections) moves through the body in people who are critically ill versus those who are not. It may help doctors choose safer and more accurate dosing for patients with blood-related illnesses.
LeuvenAges 18 years+ - NCT07420946Recruiting
Expert opinions on a lung clearance device for ICU patients
This study gathers expert opinions from healthcare professionals about using a device called MI-E to help clear airways in critically ill patients. If you are a clinician with experience in this area, your input could help shape future guidelines.
NaplesAges Any age - NCT03810768Recruiting
Metabolomics study of ICU-acquired weakness after surgery
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
Vienna, State of ViennaAges 18 years+ - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT06006000Recruiting
Supporting recovery after ICU stay for older adults
This study looks at the needs of older adults (65+) after a serious ICU stay. The goal is to help people recover better at home with support from a family or friend caregiver.
New Haven, ConnecticutAges 65 years+ - NCT06727903Recruiting
Predicting survival for older ICU patients
This study aims to create a tool to predict survival in older adults (75+) who are admitted to the ICU from the emergency room. It may help doctors better understand individual risks and make more informed care decisions.
Badalona, BarcelonaAges 75 years+ - NCT07076524Recruiting
Muscle wasting and swallowing in critically ill patients
This study looks at muscle loss and swallowing problems in very ill patients on breathing machines in the intensive care unit. It aims to understand these issues better, which could help improve care for future patients.
LondonAges 18 years+ - NCT07345169Recruiting
Immune and inflammation study in ICU patients
This study looks at how your immune system and inflammation affect your recovery in the intensive care unit. Researchers want to understand why some patients do better than others.
ParisAges 18 years+ - NCT07478367Recruiting
Muscle weakness in hospitalized patients outside the ICU
This study looks at muscle weakness that can develop when you are in the hospital for an acute illness but not in the intensive care unit (ICU). It aims to understand how common this weakness is and what factors might be involved.
RozzanoAges Any age - NCT07510776Recruiting
Understanding long-term critical illness
This study looks closely at patients who stay in the ICU for 5 days or more to understand why some people recover more slowly. It may help doctors find better ways to support you during and after a long ICU stay.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07585500Recruiting
Virtual Reality to Help Recovery in ICU Patients
This study tests whether using virtual reality (VR) glasses can help patients recover better after spending time in the intensive care unit. The VR program is designed to help regain strength, movement, and mental function during recovery.
Porto, Porto DistrictAges 18 years+ - NCT07059988Recruiting
How the body makes energy in critical illness
This study looks at how the body produces energy in critically ill patients on breathing machines. It compares energy production between ICU patients and healthy volunteers to find better ways to support recovery.
StockholmAges 18 years+ - NCT04045366Recruiting
Study drug levels in ICU patients on antifungals
This study looks at how two antifungal medicines (anidulafungin and caspofungin) behave in the blood of critically ill ICU patients. It may help doctors better understand which dosing works best when patients have low blood protein levels or fluid leakage.
LeuvenAges 18 years+ - NCT05829317RecruitingPhase 4
Magnesium to prevent new atrial fibrillation in ICU patients
This trial tests whether giving magnesium can lower the chance of developing new irregular heartbeat (atrial fibrillation) in critically ill adults in the ICU. If you are at risk but do not already have this rhythm issue, magnesium may help prevent it.
Hamilton, OntarioAges 18 years+ - NCT06751043Recruiting
Testing if fasting before a procedure is needed in ICU patients
This trial tests whether not eating before a procedure (called preoperative fasting) is better than fasting in ICU patients who are already receiving tube feedings. It aims to find out if skipping the fast can help you without causing extra risks.
Palo Alto, CaliforniaAges 18 years+ - NCT07521111Recruiting
Stomach Blood Flow and Feeding Tolerance in Critical Illness
This study examines whether measuring blood flow in the stomach using ultrasound can predict which hospitalized patients will struggle to tolerate tube feeding. Researchers hope this simple test might help doctors adjust feeding plans earlier and improve patient outcomes.
ShanghaiAges 18 years+ - NCT07108179Enrolling by invitation
Continuous glucose monitor accuracy in ICU patients
This trial tests a continuous glucose monitoring system for people in the intensive care unit (ICU). It checks how well the device measures blood sugar and if it can help predict outcomes for critically ill patients.
Changsha, changshaAges 18 years+ - NCT06536231Recruiting
Remote ischemic conditioning in ICU patients
This study tests a simple, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff to briefly stop blood flow to one arm) to see how it affects heart and blood flow in critically ill patients in the ICU. If you are in the ICU, over 18, and have a special heart monitor, you may be able to join.
KaunasAges 18–85 - NCT06533787Recruiting
Heart ultrasound in sick newborns in the NICU
This study tests how using a heart ultrasound (echocardiography) can help doctors better manage care for very sick newborns in the NICU. It may help guide treatment for babies who are unstable, regardless of their weight or how early they were born.
SohagAges 2 hours–4 weeks - NCT07178626Enrolling by invitation
Biomarkers and feeding tolerance in ICU patients
This study looks at whether certain biomarkers and stomach motility measurements can help predict feeding intolerance in critically ill patients who cannot eat by mouth. It aims to improve how patients are fed in the ICU.
ChangchunAges 18 years+ - NCT03188796RecruitingPhase 3
High-dose vitamin D for ICU patients with low vitamin D
This trial tests whether giving a high dose of vitamin D3 can reduce death within 28 days for critically ill adults in the ICU who have very low vitamin D levels. It may help by correcting vitamin D deficiency, which the study team thinks could affect outcomes in serious illness.
EnzenbachAges 18–100
Hear when a new Critical Illness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Critical Illness trials by city
Studies with a site in or near these metro areas.
Critical Illness trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 355 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.