Stem cell transplant for multiple sclerosis with MS-prep chemotherapy
Treatments studied
Part of Brain & nervous system, Immune system & allergy clinical trials.
This early-phase study tests a stem cell transplant procedure for people with multiple sclerosis whose usual MS medicines have not worked or can’t be tolerated. The goal is to see if this approach can help control MS activity and progression, while checking for safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 65
- Your MS has a disability score (EDSS) between 1.0 and 6.5
- You had MS progression in the last 6 months despite MS medicines, and you’ve had an autoimmune-disease diagnosis before
- You cannot use, can’t tolerate, or did not respond to standard MS disease medicines
- Your heart and lungs are strong enough (heart pumping strength above 50% and lung function not too low)
- You are not pregnant and can sign consent (or your legal representative can)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if using your own stem cells can stop multiple sclerosis that keeps getting worse despite treatment. You would first receive a medication to reset your immune system, then get your stem cells back to help rebuild it.
This Phase 1/2 trial studies whether donated umbilical cord stem cells are safe and can improve multiple sclerosis. It aims to see if the treatment is workable for people who still have active MS despite standard therapies.
This trial tests a new cell therapy called SYS6020 for people with multiple sclerosis that has not improved with standard treatments. The goal is to see if it can slow or stop the disease and improve symptoms.
This early phase trial tests a new treatment called GC012F for people with multiple sclerosis. It aims to see how safe and tolerable it is, and may offer a new option for those whose current treatments are not working well enough.
This early study tests whether an IV infusion of donor-derived stem cells is safe for people with multiple sclerosis. It mainly focuses on side effects and safety, not whether it improves MS symptoms yet.
This study tests whether a donor bone marrow transplant (allogeneic hematopoietic cell transplantation) can stop or slow the progression of primary progressive multiple sclerosis. It is for people with worsening symptoms who have not responded to other treatments.
Hear when a new Multiple sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.