Clin2
NCT05847179Possibly a fitRecruiting

Treating bone weakness in Werner syndrome

Werner Syndrome

Part of Genetic & congenital, Hormones & metabolism clinical trials.

This study tests an investigational drug for people with Werner syndrome who have weak bones (osteopenia or osteoporosis). The goal is to see if the drug is safe and can help improve bone health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
5 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have a confirmed diagnosis of Werner syndrome through genetic testing.
  • You must have low bone density (osteopenia or osteoporosis).
  • You must be willing to use birth control during the study and for 90 days after treatment.
  • You must be able to follow study procedures and give written consent.
  • You must not have had treatment with an experimental drug within the last 30 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05228262Recruiting
Testing blood-vessel function and muscle strength in osteoporosis

This study looks at how well your blood vessels work and how strong your muscles are, in women after menopause with osteoporosis. You may be asked to start standard osteoporosis treatment, and the researchers will study pain and changes related to vascular function and sarcopenia (loss of muscle and strength).

Clermont-Ferrand
NCT07056478Not yet recruiting· Phase 3
Studying a drug to preserve muscle in older hip fracture patients

This trial tests a drug that may help older people who break a hip and have low muscle mass (sarcopenia). It aims to see if the drug can help preserve muscle strength and speed up recovery after surgery.

Hong Kong
NCT07191353Recruiting· Phase 2
Bone strength study: weight training and a drug for bone health

This trial tests whether combining resistance training with the drug rapamycin can improve bone formation in postmenopausal women who have lower-than-normal bone density but not osteoporosis. It aims to find a new way to strengthen bones and prevent fractures.

Bispebjerg, Region Sjælland
NCT05202678Recruiting
Check a new therapy for osteoporosis-related hip bone loss

This trial studies AGN1 LOEP, a treatment being tested to improve bone strength in people with osteoporosis-related bone loss in the hip. If you qualify, you would be followed over time with clinic visits and testing to see how the treatment affects your bone health.

Sint-Niklaas, Antwerpen
NCT07062588Recruiting· Phase 2
AGA2115 for osteogenesis imperfecta in adults with COL1A1/COL1A2 variations

This trial tests a new drug called AGA2115 for people with osteogenesis imperfecta (also known as brittle bone disease) who have a confirmed genetic change in the COL1A1 or COL1A2 genes. The study aims to see if the drug can help strengthen bones and reduce fracture risk.

Phoenix, Arizona
NCT07541209Recruiting· Phase 1/Phase 2
Safety and Efficacy of PTH-IA for Rare Genetic Bone Disorder

This trial tests a new medication called PTH-IA for people with a specific genetic mutation affecting the parathyroid hormone receptor. The study aims to see if the medication is safe and can help improve bone health in children and adults with this rare condition.

Bethesda, Maryland

Hear when a new Werner Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.