Vosoritide for taller growth in girls with Turner syndrome
Treatments studied
Part of Bones, joints & muscles, Genetic & congenital, Heart & circulation, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 study tests vosoritide to help children with Turner syndrome grow taller before puberty. You may be able to join if your child is pre-pubertal, has short height for age, and either has not tried growth hormone or has not responded well to it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child’s age must be more than 3 years old and less than 10 years (3 years to 9 years, 364 days).
- A parent/guardian can give written consent, and the child can also agree (assent) if required.
- Your child must have confirmed Turner syndrome from chromosome testing (karyotype or chromosomal microarray).
- Your child must be pre-pubertal (Tanner Stage 1—no breast development).
- Your child’s height must be very short for age (below -2 “SDS” on the CDC growth charts).
- Your child must be growth-hormone “naïve” or have had at least a year of growth hormone with poor growth response, and must not currently be taking growth hormone or IGF-1, estrogen, GnRH blockers, aromatase inhibitors, or oxandrolone.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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