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NCT05885503Possibly a fitRecruiting

Testing an eye injection for diabetic macular swelling

Diabetic Macular Edema

Treatments studied

Part of Eyes & vision clinical trials.

This Phase 3 study compares a new eye injection (RC28-E) with the standard treatment (aflibercept) for diabetic macular edema, which is swelling in the central retina that affects vision. It aims to see whether the new treatment works as well and is safe.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
316 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have type 1 or type 2 diabetes.
  • Your most recent hemoglobin A1c is 10% or lower within 2 months.
  • You can attend all study visits and eye testing on the schedule.
  • In the study eye, you have diabetic macular edema that involves the center of the fovea.
  • Your best corrected vision in the study eye is 19 to 78 letters (it must be low mainly because of the swelling).
  • You should not have recent laser or recent anti-VEGF injections in the required time windows.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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