Clin2
NCT05802329Possibly a fitRecruiting

Testing eye injections for diabetic macular swelling

Center Involved Diabetic Macular EdemaDiabetic Macular Edema

Part of Eyes & vision, Hormones & metabolism clinical trials.

This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have type 1 or type 2 diabetes
  • Your main vision problem is center diabetic macular edema (DME), confirmed by an eye scan
  • Your DME thickness on the scan is within a specific range, based on the imaging machine used
  • Your vision test score is between 24 and 78 letters on an eye chart
  • You have not had anti-VEGF shots recently (or you had no prior shots, or you have had at least 2 shots with incomplete swelling improvement) and the last shot was at least 6 weeks ago
  • Your diabetes is reasonably controlled (HbA1c must be under 10%)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07459829Not yet recruiting· Phase 2
Study of an experimental drug for diabetic macular edema

This trial tests an investigational drug called CU06-1004 for people with diabetic macular edema (swelling in the center of the retina caused by diabetes). It aims to see if the drug can improve vision and reduce swelling.

NCT05885503Recruiting· Phase 3
Testing an eye injection for diabetic macular swelling

This Phase 3 study compares a new eye injection (RC28-E) with the standard treatment (aflibercept) for diabetic macular edema, which is swelling in the central retina that affects vision. It aims to see whether the new treatment works as well and is safe.

Beijing, Beijing Municipality
NCT07553429Recruiting· Phase 1/Phase 2
Testing a new eye injection for diabetic swelling

This study tests different doses of a new medicine (BI 3812465) injected into the eye to treat diabetic macular edema—swelling in the back of the eye caused by diabetes that can blur vision. The trial measures how safe the medicine is and how well patients tolerate it.

Phoenix, Arizona
NCT07425522Recruiting· Phase 1
Testing a new eye injection for diabetic macular edema

This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.

Peoria, Arizona
NCT06984822Recruiting
Comparing eye injections for diabetic macular edema

This study compares two different eye injection treatments for diabetic macular edema (DME)—a condition where fluid builds up in the center of the retina, blurring vision. Researchers want to see how certain measures in the blood and in eye scans relate to how well each treatment works.

Mölndal
NCT04187443Recruiting· Phase 1
Drug MS-553 for diabetic eye swelling with reduced vision

This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.

Changsha, Hunan

Hear when a new Center Involved Diabetic Macular Edema trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.