Immunotherapy with prednisone and sirolimus for transplant skin cancer
Treatments studied
Part of Cancer, Infections, Skin clinical trials.
This early-phase study tests whether adding immunotherapy (nivolumab and ipilimumab) to prednisone and sirolimus can control advanced skin cancers in people with kidney transplants. It aims to see how well the treatment works and how safe it is for transplant recipients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a kidney transplant that is working well, and you are not on dialysis
- You are 18 years or older (this study excludes children)
- You have a confirmed non-uveal melanoma, basal cell cancer, Merkel cell cancer, or cutaneous squamous cell cancer that cannot be handled well with standard local treatment
- Your cancer has at least one measurable spot on scans or exam
- Your blood counts and organ blood tests meet minimum lab thresholds
- You must be able to sign informed consent and follow contraception rules if you can become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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