Clin2
NCT05901324Possibly a fitNot yet recruiting

Lenalidomide maintenance for brain and eye lymphoma

Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma

Part of Brain & nervous system, Cancer, Eyes & vision clinical trials.

This trial tests whether taking lenalidomide after initial treatment helps keep primary central nervous system lymphoma or primary vitreoretinal lymphoma from coming back. It is for patients who have finished standard chemotherapy and radiation and are in remission.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older and have been diagnosed with a certain type of lymphoma in the brain or eye.
  • You have completed standard chemotherapy and radiation and your disease is in remission (complete or partial response).
  • You are able to have MRI scans and spinal taps (or a special port for medication).
  • Your major organs (heart, lungs, liver, kidneys) and bone marrow are working well enough.
  • You are able to take oral medication and are willing to use effective contraception if needed.
  • You have not had lenalidomide or whole-brain radiation before, and you are not planning a stem cell transplant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05260619Recruiting· Phase 2
Lenalidomide after response for primary brain lymphoma

This trial studies lenalidomide taken after your first treatment has worked for primary central nervous system lymphoma (PCNSL). It aims to help keep the lymphoma from coming back by testing lenalidomide as ongoing “maintenance” treatment.

Seongnam-si, Please Select
NCT04627753Recruiting· Phase 2
Lenalidomide plus rituximab to prevent brain lymphoma return

This trial studies whether lenalidomide and rituximab can help keep primary CNS lymphoma from coming back after initial chemotherapy. It may be an option if you cannot do a transplant and you can take pills.

Seoul
NCT06175000Recruiting· Phase 2
Maintenance obinutuzumab for central nervous system lymphoma

This trial tests whether a maintenance drug called obinutuzumab can help prevent relapse in people with primary central nervous system lymphoma (a rare lymphoma in the brain or spine) who have already responded to initial chemotherapy. It is for those who have achieved at least a partial or complete response to their first treatment.

New York, New York
NCT05351593Recruiting· Phase 1/Phase 2
Tafasitamab and lenalidomide for returning CNS lymphoma

This trial tests a combination of two drugs, tafasitamab and lenalidomide, for people whose central nervous system lymphoma has come back. The goal is to see if this treatment can help shrink the cancer or slow its growth.

San Francisco, California
NCT06737250Recruiting· Phase 2
Testing a new drug combo for relapsed brain lymphoma

This trial tests a combination of three drugs (poseltinib, rituximab, and lenalidomide) for people with primary central nervous system lymphoma that has come back or not responded to earlier treatment. The goal is to see if this new mix can help control the disease.

Busan
NCT06931652Recruiting· Phase 2
Epcoritamab with lenalidomide and rituximab for CNS lymphoma

This trial tests a new combination of drugs—epcoritamab, lenalidomide, and rituximab—for people with primary central nervous system lymphoma (PCNSL) that has come back or not responded to treatment. The goal is to see if this three-drug therapy can help control the cancer.

Bordeaux

Hear when a new Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.