Clin2
NCT05910177Possibly a fitRecruiting

Pre-surgery treatment for cervical neuroendocrine cancer with immunotherapy

CarcinomaCervix Carcinoma

Part of Cancer, Women’s health & pregnancy clinical trials.

This Phase 2 trial tests giving camrelizumab plus chemotherapy (etoposide and cisplatin) before surgery for certain cervical neuroendocrine cancers. It aims to shrink the tumor and improve outcomes by treating cancer early rather than waiting until after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are a woman age 18 to 75 with cervical neuroendocrine cancer confirmed by pathology or cytology
  • Your cancer is FIGO stage I or II, and a surgeon believes it can be removed with an operation
  • Your scans show a measurable tumor area (certain minimum sizes on CT), meaning it can be tracked
  • You must be able to perform daily activities fairly normally (ECOG 0 to 1) and expected survival is more than 3 months
  • Your blood, liver, kidney, and clotting tests must be within required safety ranges

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07055399Recruiting· Phase 2
Neoadjuvant immunotherapy with two drugs plus chemo for cervical cancer

This trial tests two immunotherapy drugs (iparomlimab and tuvonralimab) combined with chemotherapy before surgery for locally advanced cervical cancer. It aims to shrink tumors and improve outcomes for patients who haven't had prior systemic treatment.

Fuzhou, Fujian
NCT07104149Recruiting· Phase 2
Chemo plus immunotherapy before surgery for cervical cancer

This trial tests adding a new immunotherapy drug (cadonilimab) to standard chemotherapy before surgery for locally advanced cervical cancer. The goal is to see if this combination helps shrink the tumor more effectively before surgery.

Zhengzhou, Henan
NCT06288373Recruiting· Phase 2/Phase 3
Comparing chemoimmunotherapy vs chemoradiation for advanced cervical cancer before surgery

This trial tests whether a combination of chemotherapy and immunotherapy (pembrolizumab) before surgery works better than standard chemoradiation for locally advanced cervical cancer. It may help shrink tumors more effectively.

Hefei, Anhui
NCT06289062Recruiting· Phase 2
Chemo plus camrelizumab before surgery for stage IB1 cervical cancer

This trial tests whether giving chemotherapy combined with camrelizumab (a drug that helps the immune system fight cancer) before surgery can help women with early-stage cervical cancer who want to preserve their fertility. It is for patients whose tumors show a protein called PD-L1.

Guangzhou, Guangdong
NCT06288360Recruiting· Phase 2
Chemo plus immunotherapy before surgery for PD-L1-negative cervical cancer

This trial tests whether combining chemotherapy with immunotherapy before surgery can help treat cervical cancer that is PD-L1 negative. It's for women with larger tumors (stage IB3 to IIB) who have not been treated yet.

Hefei, Anhui
NCT06289751Recruiting· Phase 2
Chemo-immunotherapy before surgery for stage IB2 cervical cancer

This trial tests if giving chemotherapy plus an immunotherapy drug before surgery can help shrink tumors and improve outcomes for patients with stage IB2 cervical cancer that has not been treated yet. It might be an option if you have a specific type of cervical cancer that shows a certain protein (PD-L1) on your tumor cells.

Wuhan, Hubei

Hear when a new Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.