Allopurinol to lower heart and stroke risks in high-risk people
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether allopurinol can reduce the chance of cardiovascular events like heart attack, stroke, or related problems in people who are at higher risk. It targets people with higher uric acid and other risk factors, to see if lowering uric acid helps protect the heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 40 and 70 years old.
- Have signed consent to join the study.
- Have a uric acid level above 5 mg/dL in blood tests within the last 6 months.
- Be at high cardiovascular risk (for example, higher 10-year risk score, known heart/brain blood vessel disease, atrial fibrillation, heart failure in early stages, peripheral artery disease, or diabetes/high blood pressure with organ damage signs).
- Not currently take allopurinol, febuxostat, or any other uric-acid–lowering medicine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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