Compare urate targets to reduce gout attacks or symptoms
Treatments studied
Part of Bones, joints & muscles, Genetic & congenital, Hormones & metabolism clinical trials.
This study compares two different treatment goals for a blood level called urate in people with gout. The goal is to see which approach lowers gout flares better while helping people feel better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You agree to sign informed consent (paper or electronically).
- You are 18 to 90 years old.
- You see a participating primary care clinic at least once in the last 3 years.
- Your gout diagnosis fits standard criteria, and your score is high enough (at least 8).
- You have had at least one gout flare in the last 12 months and your recent urate level is at least 6.0 mg/dL.
- You can swallow pills and you follow birth control rules if you could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares a new gout medicine called dotinurad to the common medicine allopurinol. It is for people who have had gout for at least a year, have had at least 2 gout attacks in the last year, and are already taking a stable dose of allopurinol but still have high uric acid levels.
This trial tests whether starting dotinurad, a medication that lowers uric acid, at different times after a gout flare begins can help the flare resolve faster. It may help people with frequent or severe gout attacks find quicker relief.
This study tests whether a pharmacist-led program can help veterans with gout better manage their uric acid levels using common medications like allopurinol or febuxostat. If you have had a gout flare in the last 6 months and are already taking or starting a urate-lowering medication, this trial may be for you.
This study tests two doses of a medicine called Purified Cortrophin Gel for people having a gout flare that started in the last 5 days. It might be an option if other treatments haven't worked or aren't safe for you.
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
This trial tests a new medicine called tigulixostat against febuxostat, a standard gout treatment, to see which works better at lowering uric acid levels. You may qualify if you have gout with high uric acid and have not had a gout flare in the last month.
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