Clin2
NCT05951231Possibly a fitNot yet recruiting

Liver transplant using a donor liver kept alive outside the body

Liver Transplant; ComplicationsTransplant; Failure, LiverTransplant DysfunctionTransplant; Complication, RejectionTransplantLiver MetastasesLiver Cancer

Part of Cancer, Digestive system clinical trials.

This trial studies whether using an “ex vivo perfusion” process—keeping a donor liver alive outside the body before transplant—can improve outcomes for certain people who need a liver transplant but have limited options. It may help patients who are too high-risk for standard transplant timing or options, including some cancer-related liver disease cases.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
22 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You are an adult (18 or older) and can sign informed consent
  • You need a liver transplant for an eligible reason (includes specific cancer types, urgent benign liver disease, or life expectancy of 6 months or less)
  • If cancer-related, your overall physical status is good (ECOG 0 or 1, as decided by your treating team)
  • Your blood tests must be within allowed ranges (including hemoglobin, neutrophils, platelets, bilirubin, and liver enzymes)
  • You must be willing and able to come for follow-up visits during the study
  • You are not already expected to receive a regular donor liver soon, and you are not in certain related liver-transplant studies

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03946852Not yet recruiting
Testing a new blood-boost method for liver transplants after cardiac death

This study tests whether a special way of moving blood through the donor abdomen before surgery can improve liver (and other organ) transplant quality. It may help because doctors can check how well the liver seems to be working before it’s actually used.

NCT04616495Recruiting
Liver transplant for colorectal cancer that can’t be removed

This trial studies liver transplantation for people with colorectal cancer that has spread to the liver but cannot be surgically removed. It aims to see if transplant can improve outcomes when the cancer is limited to the liver.

Valencia
NCT05398380Recruiting
Liver transplant for colorectal liver cancer that can’t be removed

This trial studies liver transplantation for certain people with colorectal cancer that has spread only to the liver and cannot be removed with surgery. It aims to improve outcomes for carefully selected patients whose cancer is controlled on chemotherapy and who meet specific safety and scan requirements.

Barcelona, Barcelona
NCT02864485Recruiting
Living donor liver transplant for colorectal cancer spread to the liver

This trial looks at whether a living-donor liver transplant can help people with colorectal cancer that has spread to the liver but cannot be surgically removed. It focuses on people whose cancer has not worsened on prior chemotherapy and who are medically able to undergo a major liver surgery.

Toronto, Ontario
NCT03494946Recruiting
Liver transplant vs chemotherapy for colon cancer liver spread

This trial compares liver transplantation to standard chemotherapy for people with colon or rectal cancer that has spread to the liver but cannot be removed surgically. It looks at whether transplant can help patients live longer or better than chemotherapy in the right patients.

Oslo
NCT06236568Recruiting
Liver transplant study for liver cancer patients

This study tests a special way to preserve donated livers before transplant to see if it reduces the chance of liver cancer coming back after surgery.

Modena, MO

Hear when a new Liver Transplant; Complications trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.