Liver transplant surgery after chemotherapy or stable liver cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a two-step liver surgery approach for people with advanced (not fully removable) liver cancer or end-stage liver disease, using chemotherapy first when applicable. The goal is to see if this staged plan can better control disease and allow safer surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 75 years old
- Have either (1) liver cancer that cannot be fully removed (unresectable) with spread to the liver, or (2) end-stage liver disease
- If you have cancer: after 6–8 weeks of first chemotherapy, the tumor should not have significantly grown (it may shrink but must still be unresectable), and there should be no other abdominal spread (except possibly 1–3 removable lung metastases)
- Have liver function rated Child-Pugh A or B, and be well enough to undergo a planned surgery program
- Be able to get through required medical care and follow instructions; agree to sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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