Sirolimus stent for severe blocked leg arteries
Part of Heart & circulation clinical trials.
This trial tests a special stent-like device placed in blocked arteries below the knee to improve blood flow in people with critical limb ischemia. If you meet the artery and health requirements, the goal is to reduce artery re-blocking and help prevent worsening leg problems over 12 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 to 85 and able to understand the study and sign consent (including follow-up for 12 months).
- Have severe, painful or dangerous poor blood flow in the leg (critical limb ischemia) with Rutherford stage 3–5.
- Need first treatment for new (de novo) artery blockages below the knee.
- Your blockage should be very narrow or fully blocked in up to two below-knee arteries, and the treated area must be in specific locations and sizes.
- You must have at least one artery to the ankle that is not badly blocked (less than 30%).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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