Clin2
NCT05975580Possibly a fitRecruiting

Medication plus lifestyle counseling for weight regain after bariatric surgery

Obesity

Treatments studied

Part of Hormones & metabolism clinical trials.

This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
120 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You’re 18 to 70 years old.
  • You had sleeve gastrectomy or Roux-en-Y gastric bypass at least 18 months ago.
  • Your weight has gone up by at least 5% compared with your lowest weight after surgery.
  • Your BMI is at least 30, or at least 27 with a weight-related health problem.
  • You can share signed consent and follow study instructions; if you can become pregnant, you must use reliable birth control and have a negative pregnancy test at the start.
  • You must not have certain medical and mental health conditions (for example, uncontrolled diabetes, unstable heart disease, psychosis/bipolar disorder, recent unstable depression, or recent alcohol/drug misuse).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06484621Recruiting
Preventing weight regain after weight loss surgery with exercise

This study looks at whether increased physical activity can help prevent weight regain after weight loss surgery. It is for people who had gastric bypass or sleeve gastrectomy in the last 6–20 months and have regained less than 10% of their lost weight.

Hartford, Connecticut
NCT06292936Recruiting
Remi for weight regain after weight loss surgery

This study tests if the medication Remi can help people who have gained back at least 5% of their lowest weight after gastric bypass or sleeve gastrectomy. It is meant for those who are not currently using other weight loss drugs and are otherwise healthy enough to participate.

Chicago, Illinois
NCT05242835Recruiting
Study for weight regain after sleeve stomach surgery

This trial studies a specific type of metabolic (weight-related) surgery for people whose sleeve gastrectomy did not lead to enough weight loss or has caused significant weight regain. It may help improve long-term weight and related health problems.

Québec, Quebec
NCT07732738Recruiting
Bariatric surgery plus GLP-1 drug for weight loss and diabetes

This study tests if adding a GLP-1 medication to weight-loss surgery helps people with obesity and related conditions like diabetes. It may improve weight loss and blood sugar control more than surgery alone.

Xingtai, Hebei
NCT07336862Recruiting· Phase 1/Phase 2
Weight loss surgery plus GLP-1 drug for obesity and diabetes

This trial tests whether adding a GLP-1 receptor agonist (a medication that helps control blood sugar and appetite) after weight loss surgery improves outcomes for people with severe obesity and related health problems like type 2 diabetes.

Beijing
NCT06511310Recruiting
Exercise, brain health, and weight maintenance after weight loss surgery

This study looks at how exercise affects brain activity and helps people keep weight off after they have regained some weight following bariatric surgery. You may join if you had weight loss surgery, lost weight, and then regained more than 10% of that lost weight within the last 1 to 5 years.

Boston, Massachusetts

Hear when a new Obesity trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.