Measuring methadone doses for chronic pain
Part of Pain clinical trials.
This trial is for people with chronic pain who take daily methadone. It aims to measure how much methadone is in your body to help doctors find the right dose.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 70 years old.
- You have a prescription for methadone to treat chronic pain, not addiction.
- You take at least 10 mg of methadone every day and have been for at least a week.
- You have taken your methadone exactly as prescribed for the last 4 days.
- You do not have any serious health conditions like kidney failure, liver disease, or cancer.
- You are not pregnant, planning pregnancy, or in a substance use treatment program.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a small patch that checks methadone levels in your sweat to make sure you're getting the right dose. It might help you and your doctor manage your treatment more easily from home.
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
This study tests whether giving a single dose of methadone during surgery can improve pain relief after the operation, possibly reducing the need for other painkillers and helping you recover more comfortably. It is for people having certain planned surgeries that require an overnight stay in the hospital.
This study compares taking methadone as one dose versus split into two doses to see which approach works better for people who have pain. It’s meant for adults already on a steady methadone program and who can follow study visits and procedures.
This study measures how methadone moves through your body by using planned blood samples and computer modeling. It may help doctors better predict methadone levels to support safer dosing for people already taking methadone.
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hear when a new Drug Metabolism, Poor, CYP2D6-Related trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.