Fluzoparib, Camrelizumab, and Temozolomide for advanced melanoma
Part of Cancer, Skin clinical trials.
This trial tests a combination of three drugs (Fluzoparib, Camrelizumab, and Temozolomide) for people with advanced melanoma that has spread or cannot be removed by surgery. It is for those who have a specific genetic change (HR or SF3B1 mutation) and have not been treated with a PARP inhibitor before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced melanoma (stage III or IV) that cannot be removed by surgery or has spread
- You have a specific genetic change called HR or SF3B1 mutation in your tumor
- You have not been treated with a PARP inhibitor drug before
- You are generally able to perform daily activities (ECOG score 0 or 1)
- You have recovered from side effects of previous treatments
- You are willing to use birth control if needed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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