Can a Blood Test Replace Biopsy for Celiac Disease?
Part of Digestive system, Hormones & metabolism clinical trials.
This study looks at whether a simple blood test (tTG-IgA) can diagnose celiac disease without needing a biopsy. It includes children and adults who eat gluten and have certain blood test results.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be eating a gluten-containing diet (not gluten-free).
- You must have a positive blood test for IgA anti-tissue transglutaminase (tTG-IgA) or a special cell test (TCR gamma delta).
- You must not already have a confirmed celiac disease diagnosis.
- You cannot have a weakened immune system (primary or secondary immunodeficiency) or active cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at why some adults with celiac disease still have damage to their small intestine even after strictly avoiding gluten. It aims to understand persistent villous atrophy and could help improve long-term care for people like you.
This study looks at better ways to diagnose celiac disease, a condition where eating gluten damages your small intestine. If you've recently had an endoscopy and a celiac blood test, your information could help improve how doctors diagnose this condition.
This study uses ultrasound and blood tests to check how active celiac disease is, which may help doctors monitor the condition without needing invasive procedures.
This study tests a new medicine called HB-2121 used as a diagnostic tool during an upper endoscopy to help improve detection of celiac disease. It's designed for people who are already scheduled for this procedure and may help doctors see the gut damage caused by celiac more clearly.
This trial compares different forms of gluten to see which one causes the strongest immune reaction in people with celiac disease. It may help doctors choose the best way to test gluten sensitivity in the future.
This research study examines tissue samples from your small bowel (the part of your digestive system after your stomach) to better understand celiac disease and related conditions. By studying these samples in detail, researchers hope to improve how doctors diagnose and treat small-bowel diseases.
Hear when a new Celiac Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.