Can a Blood Test Replace Biopsy for Celiac Disease?
Part of Digestive system, Hormones & metabolism clinical trials.
This study looks at whether a simple blood test (tTG-IgA) can diagnose celiac disease without needing a biopsy. It includes children and adults who eat gluten and have certain blood test results.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be eating a gluten-containing diet (not gluten-free).
- You must have a positive blood test for IgA anti-tissue transglutaminase (tTG-IgA) or a special cell test (TCR gamma delta).
- You must not already have a confirmed celiac disease diagnosis.
- You cannot have a weakened immune system (primary or secondary immunodeficiency) or active cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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