Clin2
NCT05991102Possibly a fitRecruiting

Radiofrequency treatment with Lonsurf and Avastin for advanced colorectal cancer

Refractory Metastatic Colorectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial tests if adding a special radiofrequency treatment to the drugs Lonsurf (TAS-102) and Avastin (bevacizumab) can help people whose colorectal cancer has spread to the liver and has not responded to previous treatments. It is for patients with limited options who have already tried at least two standard chemotherapy regimens.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
12 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer that has spread to your liver.
  • You have already tried at least two standard chemotherapy treatments and they no longer work or you cannot take them.
  • You are 18 years or older and able to take pills by mouth.
  • You are in reasonably good health (able to do daily activities without major assistance).
  • Your blood counts and kidney/liver function are at safe levels as determined by blood tests.
  • You have no other serious health conditions like active infections, heart problems, or other cancers that are not well-controlled.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06764680Recruiting· Phase 2
Oral drugs and radiation for advanced colorectal cancer after standard therapy

This trial tests a combination of oral chemotherapy, targeted therapy, and immunotherapy, with or without radiation, for people with advanced colorectal cancer that hasn't responded to at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow the disease.

Guangzhou, Guangdong
NCT07391566Not yet recruiting· Phase 1/Phase 2
Study drug with chemotherapy for advanced colorectal cancer

This trial tests a new drug combined with standard chemotherapy and another medication for people with advanced colorectal cancer that has a specific genetic change (RAS mutation). It aims to see if the combination can help control the cancer better.

Beijing
NCT06563986Recruiting· Phase 2
Combination therapy for advanced colorectal cancer in the liver

This trial tests a combination of two chemotherapy drugs (FTD and tipiracil), a targeted therapy (bevacizumab), and a radiation treatment (radioembolization) for people with colorectal cancer that has spread mainly to the liver and hasn't responded to other treatments. The goal is to see if this combination can shrink tumors and help control the cancer.

Utrecht
NCT07123441Not yet recruiting· Phase 2
Combination therapy for advanced colorectal cancer

This trial tests a new combination of drugs (liposomal irinotecan, 5-FU/LV, and bevacizumab) for people with advanced colorectal cancer that cannot be removed by surgery. The goal is to see if this treatment is safe and effective in shrinking tumors and improving outcomes.

Shanghai, Shanghai Municipality
NCT07797244Not yet recruiting· Phase 2
Combination treatment for advanced colorectal cancer with liver spread

This trial tests a new drug (retlirafusp alfa) combined with two chemotherapy drugs and a targeted therapy (bevacizumab) for people with advanced colorectal cancer that has spread to the liver and has a specific gene change (RAS mutation). It aims to see if this combination can shrink tumors and improve outcomes in people who have not had prior treatment.

Beijing, Beijing Municipality
NCT05747716Not yet recruiting· Phase 2
Targeted radiation plus immunotherapy for advanced colorectal cancer

This study tests a combination of precisely targeted radiation (SBRT) with two drugs: fruquintinib (a pill that blocks blood supply to tumors) and antibodies that boost your immune system to fight cancer (PD-1 and CTLA-4 inhibitors). It is for people with advanced colorectal cancer who have already tried two standard chemotherapy treatments.

Wuhan, Hubei

Hear when a new Refractory Metastatic Colorectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.