Reducing rituximab doses in rheumatoid arthritis
Treatments studied
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This trial compares two ways to reduce the amount of rituximab you take: one that gradually gives it less often based on time, and another that only gives it when your disease flares up. The goal is to see which approach keeps your arthritis under control while using less medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have rheumatoid arthritis and are currently being treated with rituximab.
- You have had at least one good response to a rituximab treatment cycle in the past.
- Your disease activity score (DAS28) is 3.2 or higher, meaning you need another dose of rituximab.
- You have been on a stable dose of methotrexate or other similar arthritis medications for at least 4 weeks.
- You can understand and write in Dutch or French.
- You are not pregnant or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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