Placenta study to prevent repeat pregnancy complications
Part of Women’s health & pregnancy clinical trials.
This trial tests whether a blood-thinning medication (enoxaparin) can help prevent complications like preterm birth or preeclampsia from happening again. It is for people who had a past pregnancy problem tied to placenta blood flow issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a past pregnancy problem like preterm birth (before 37 weeks), a very small baby, severe preeclampsia, or stillbirth (after 20 weeks).
- A special pathologist confirmed that your placenta from that past pregnancy had blood flow problems (called maternal vascular malperfusion).
- You are currently pregnant with one baby and your pregnancy is less than 17 weeks along.
- You are not planning to take blood-thinning medication (like enoxaparin, warfarin, or heparin) for this pregnancy.
- You do not have certain health conditions like active bleeding, low platelets, severe kidney or liver disease, or a mechanical heart valve.
- You do not have a serious fetal abnormality known already.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how people’s blood and clotting behave during pregnancy when taking a specific blood thinner called low molecular weight heparin (LMWH) three times a day. It may help doctors fine-tune how safely and effectively LMWH is used during pregnancy.
This study tests two treatments—progesterone (a hormone) and a blood thinner (low molecular weight heparin)—to see if they help women who have had repeated miscarriages carry a pregnancy to term. If you join, you may receive one or both treatments during your pregnancy.
This trial compares two blood-thinning medicines (apixaban and enoxaparin) to prevent dangerous blood clots after childbirth. If you are at higher risk for clots but not breastfeeding, you may be able to take part.
This trial tests whether a blood-thinning medicine (low molecular weight heparin) can improve pregnancy outcomes in women with protein S deficiency, a condition that raises the risk of blood clots. The goal is to see if this treatment helps prevent pregnancy complications caused by clots.
This study tests whether giving a short course of a daily blood-thinning injection (enoxaparin) after childbirth can safely prevent blood clots in women at intermediate risk. If you qualify, you would receive the injection or a placebo (inactive shot) for up to 5 days while in the hospital.
This trial studies whether tranexamic acid can prevent heavy bleeding after a planned or urgent cesarean delivery in people with placenta previa. If you qualify, you may receive the study drug to help your body keep blood loss lower during and after surgery.
Hear when a new Adverse Pregnancy Outcome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.