Pain-block injection for headache after brain bleed
Part of Brain & nervous system, Heart & circulation, Pain clinical trials.
This study tests a pain-block injection (called a PPF-block) for severe headaches after a brain bleed (subarachnoid hemorrhage). It compares the injection to standard pain medicine to see if it reduces headache and the need for opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a spontaneous brain bleed (subarachnoid hemorrhage or SAH) within the last 3 days, not caused by a head injury or infection.
- You are between 18 and 85 years old.
- You need at least 15mg of morphine-equivalent pain medicine for headache in a 24-hour period.
- If you had an aneurysm, it must be successfully treated (at least 90% closed) with a procedure like coiling or clipping.
- You are not on blood thinners (except aspirin) and have no history of regular opioid use in the past month.
- You can receive the first pain-block injection within 96 hours (4 days) of the bleed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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