Cooling treatment for cardiac arrest before hospital
Part of Heart & circulation clinical trials.
This trial tests whether cooling the brain through the nose right after a cardiac arrest improves survival. Paramedics will start a cooling treatment within 20 minutes of arriving, and it may help protect your brain while you are unconscious.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 79 years old
- Your heart started with a shockable rhythm (like ventricular fibrillation)
- You are unconscious after the cardiac arrest
- Paramedics can start the cooling treatment within 20 minutes of arriving
- The cardiac arrest is likely from a heart problem, not a non-heart cause
- You are not already hypothermic (too cold)
- You do not have a Do Not Resuscitate order or terminal illness
- You are not pregnant and there is no barrier to placing a small tube in your nose
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if starting body cooling before reaching the hospital can help protect the brain after a cardiac arrest. It is for adults who are unconscious after their heartbeat has been restored by emergency services.
This Phase 3 trial studies treatments given after a person survives an out-of-hospital cardiac arrest to improve recovery and survival. It is for patients who stay unconscious for a short time after circulation returns, and who meet safety conditions.
This trial tests a treatment that uses a blood pressure cuff on your arms to try to protect your brain and organs after your heart stopped outside the hospital. You will be in the intensive care unit, and the study will check if this simple 'remote conditioning' can improve recovery.
This trial tests if a special blood pressure cuff (like a tourniquet) placed on the leg can protect the brain after a cardiac arrest. It is for patients who are unconscious and on a breathing machine after their heart restarts.
This trial tests if gently cooling the body to 33°C after a cardiac arrest in the hospital improves recovery compared to keeping a normal temperature. It aims to protect the brain and help patients wake up better.
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
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