Immunotherapy plus chemotherapy for moderate-risk GTN
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial tests a combination of an immunotherapy drug (toripalimab) and a chemotherapy drug (actinomycin-D) as the first treatment for gestational trophoblastic neoplasia (GTN) with a FIGO score of 5-6. It may help patients whose disease is at a moderate risk level.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be diagnosed with a specific type of gestational tumor (GTN) that is not another rare type (PSTT or ETT).
- Your FIGO score must be 5 or 6 — this is a number that tells how advanced the disease is.
- You cannot have had any chemotherapy, immunotherapy, or radiation therapy before joining this trial.
- You must be between 18 and 60 years old and healthy enough to get out of bed (ECOG score 0-2).
- Your blood counts, liver, kidney, and thyroid function must be within a safe range.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of two drugs — toripalimab (an immunotherapy) and actinomycin-D (chemotherapy) — as the first treatment for a specific type of pregnancy-related tumor (GTN) with a FIGO score of 7. The goal is to see if this combination works better than standard treatment.
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This trial is creating a database for women diagnosed with gestational trophoblastic neoplasia (GTN), which includes tumors that can develop after a molar pregnancy or other pregnancy-related conditions. By joining, you help researchers better understand and improve treatment for these rare tumors.
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