Late cerclage for preventing early birth in high-risk pregnancies
Part of Women’s health & pregnancy clinical trials.
This trial tests if placing a stitch in the cervix (cerclage) between 24 and 27 weeks of pregnancy can help prevent preterm birth in women whose cervix is short. It may be an option for those who find out late in pregnancy that they are at risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old and assigned female at birth.
- You are pregnant with one baby (not twins or more).
- Your cervix is 25 millimeters or shorter, measured by ultrasound between 24 weeks and 0 days and 26 weeks and 6 days of pregnancy.
- You do not already have a cervical stitch in place.
- You have no signs of preterm labor, water breaking, active bleeding, or infection inside the uterus.
- Your baby has no major birth defects or chromosome problems, and you have no placenta previa or accreta.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether adding a cervical stitch (cerclage) to progesterone treatment helps prevent early birth better than progesterone alone in women with a short cervix.
This trial compares two types of surgery (one done through small cuts in the belly, one done through the vagina) to place a stitch around the cervix and prevent preterm birth. It may be a good option if you and your doctor are unsure which approach is best for you.
This study compares two treatments for women expecting twins who have a short cervix (less than 30mm). It looks at whether adding a cervical stitch (cerclage) to progesterone hormone therapy works better than progesterone alone to help prevent early birth and improve newborn health.
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This study tests whether placing a “cervix stitch” (cerclage) can reduce the risk of very early birth in twin pregnancies. It is for people whose cervix is shorter than expected or has started to open before 24 weeks.
This trial looks at two methods of placing a stitch in the cervix to help prevent early birth in women who have had preterm deliveries or late miscarriages before. It compares a stitch placed through the vagina versus one placed through the belly using a laparoscope (a small camera tool).
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