Clinical trials
Premature Birth clinical trials
Below are recruiting premature birth clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05114096RecruitingPhase 4
One-time steroid shot to help babies stay healthier early
This trial studies whether giving a single steroid medicine shot during pregnancy can improve outcomes when preterm birth is at risk. The goal is to help the baby’s lungs and overall health before early delivery.
Calgary, AlbertaAges 18–55 - NCT06226051Recruiting
Growing Little PEAPODS Preterm Baby Study
This study follows the growth and body composition of very premature babies (born between 22 and 32 weeks) to learn how they develop. It uses a special device called the PEAPOD to measure body fat, which may help improve care for preemies.
Madison, WisconsinAges 5 months–7 months - NCT06265740Recruiting
Using vaginal bacteria to predict early labor
This study is testing a new way to predict early labor by looking at the bacteria in the vagina. If you are pregnant and in the hospital for possible early labor or a water break, a vaginal swab could help doctors understand why this happens.
Clermont-FerrandAges 18 years+ - NCT05685745Recruiting
Hospital data collection for very early baby care
This study collects information from hospitals about babies born extremely early (22 to 23 weeks of pregnancy). It helps researchers understand what care happens and what outcomes occur, which can guide improvements in future care.
Birmingham, AlabamaAges birth–1 year - NCT07490912Recruiting
Neonatal data and biobank study for preterm infants
This study collects health information and biological samples from very premature babies to understand what affects their development. It may help researchers find ways to improve care and outcomes for infants like yours.
Cologne, North Rhine-WestphaliaAges Up to 18 years - NCT06401083RecruitingPhase 4
Extra caffeine dose before removing breathing tube in preemies
This study tests if giving an extra dose of caffeine (a medicine that helps premature babies breathe) right before removing the breathing tube can make the transition easier. It is for very premature babies who have been on a ventilator for at least two days and are ready for their first try at breathing on their own.
BudapestAges Any age - NCT06723067Recruiting
Wearable breast pump study for mothers of premature babies
This study tests if wearable, wireless breast pumps help mothers of premature infants express milk more often and effectively. Participants will be randomly assigned to use either a wearable pump or a standard hospital pump.
Austin, TexasAges Any age - NCT07570121RecruitingPhase 1
How Caffeine Moves Through Pregnancy and to the Baby
This study looks at how caffeine is absorbed and transferred to a baby during pregnancy in women at risk of early delivery. Researchers hope to understand safe caffeine use in this situation and potentially help prevent complications.
Indianapolis, IndianaAges 18 years+ - NCT07732257Recruiting
Wireless button sensor study for premature infants
This study tests a small, wireless button-like sensor to monitor vital signs in premature infants in the NICU. It may offer a gentler way to track your baby's health.
Montreal, QuebecAges Any age - NCT05397197Recruiting
Studies how early birth affects learning new words
This study looks at how being born early (between 32 and 36 weeks) or at full term affects a baby’s vocabulary learning. It also compares babies who have typical newborn health checks to better understand what might influence language development.
MarseilleAges birth–2 years - NCT05264779Recruiting
Decision help tool for very early delivery planning
This study tests a decision-support tool (a structured way to guide conversations) for parents facing a high risk of delivering very early (about 22–26 weeks). It may help you and your baby’s care team make clearer, more aligned choices about neonatal (newborn) treatment.
San Diego, CaliforniaAges 18 years+ - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT02997345Recruiting
PPROM pregnancy registry for women under 37 weeks
This registry is collecting information from pregnant people diagnosed with preterm premature rupture of membranes (PPROM) before 37 weeks. It may help researchers better understand PPROM and improve care for future patients.
Denver, ColoradoAges 14–55 - NCT06295484Recruiting
Comparing two breathing support methods for very small babies
This study compares two types of breathing support (nasal CPAP and NIPPV) for very low birth weight preterm infants to see which one works better. The goal is to find the best way to help these babies breathe more easily.
Toronto, OntarioAges 1 day–8 months - NCT05340582RecruitingPhase 2
Ibuprofen plus acetaminophen for a heart condition in very premature babies
This Phase 2 study tests whether giving ibuprofen together with acetaminophen improves outcomes for an important heart connection (PDA) in extremely premature infants. It compares how this medicine approach affects the baby’s heart-related measurements and short-term progress.
Newcastle, New South WalesAges Up to 6 months - NCT06224764Recruiting
Study on very small premature babies after going home
This study looks at how very small premature babies (born early and weighing less than 4.4 pounds at discharge) do after they go home. It helps doctors understand what support families need.
PontoiseAges 1 month–11 years - NCT07183462RecruitingPhase 4
Antibiotic treatment for late preterm water breaking
This trial tests whether a combination of two antibiotics (azithromycin and ampicillin) can help pregnant people whose water has broken between 34 and 36 weeks of pregnancy. The goal is to see if this treatment improves outcomes for both the parent and baby without causing early labor or infection.
Ramat Gan, IsraelAges 18–50 - NCT07236996Recruiting
Air purifier health effects in preterm infants after discharge
This trial tests if using an air purifier at home helps improve the health of babies who were born early (before 37 weeks of pregnancy). The goal is to see if cleaner air reduces breathing problems or other issues after they leave the hospital.
Kaohsiung CityAges Up to 6 years - NCT06624709Recruiting
Iron schedule trial for premature babies
This study tests whether giving iron supplements 4 times a week is better than daily iron for premature babies. It aims to improve hemoglobin levels at 6 months.
Geneva, Canton of GenevaAges 2 weeks–2 weeks - NCT05734768Recruiting
Study of anxiety and depression in parents after preterm birth
This study compares how parents feel (anxiety and depression symptoms) after having a baby born preterm versus a full-term baby. It also looks at early “building blocks” of thinking and social development in the child.
ReimsAges 18 years+ - NCT06022991Recruiting
Fathers and partners in preterm baby care study
This study looks at how involving fathers and partners in the care of preterm babies in the hospital can help the whole family. It aims to understand what works best for families and their babies.
LondonAges Any age - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT05969431Recruiting
Measuring hair cortisol to study stress in fathers of babies
This study looks at whether a father’s stress level over time can be estimated by measuring cortisol (a stress hormone) in hair. Results may help researchers better understand how chronic stress affects new families, especially when babies are born early or on time.
Cologne, Northrhine-westfaliaAges 1 day–1 week - NCT05319158Recruiting
Movement imitation therapy for very premature baby movement quality
This study tests whether “movement imitation therapy” can improve how a preterm baby moves. It looks at specific movement patterns in babies born very early, aiming to help motor (movement) development.
Barcelona, BarcelonaAges 5 months–7 months
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Premature Birth trials by city
Studies with a site in or near these metro areas.
Premature Birth trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for premature birth?
- Yes. Clin2 currently lists 59 recruiting premature birth studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature birth trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature birth trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.