Epcoritamab with low-intensity chemo for older or frail patients with new lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This study tests a new immunotherapy drug (epcoritamab) combined with a milder chemotherapy (rituximab-mini CVP) for older or frail patients who cannot receive standard strong chemo. It aims to effectively treat newly diagnosed diffuse large B-cell lymphoma with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- 18 years or older
- Newly diagnosed with diffuse large B-cell lymphoma (or similar types) that has not been treated yet
- Cannot get standard strong chemo due to age 80+, being frail, heart problems, or previous heart-damaging treatment
- Lymphoma is stage II bulky, III, or IV, and measurable by scans
- Adequate kidney, liver, and blood cell counts (with some allowance for support)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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