Saline enema for meconium blockage in premature babies
Treatments studied
Part of Digestive system clinical trials.
This trial tests if giving a saline enema helps premature babies with meconium blockage pass stool, start feeding, and improve gut and brain health. It may reduce complications and help babies grow better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Baby weighs between 500 and 1250 grams at birth
- Baby is at least 23 weeks into pregnancy at birth
- Baby has not passed stool for 48 hours or only passed a small amount
- Baby shows signs of feeding problems or has a belly X-ray showing blocked bowel
- Baby does not have a muscle or nerve disorder or severe birth asphyxia
- Parent or guardian gives consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a tiny enema made from the mother's own breast milk can help very premature babies pass their first stool (meconium) safely. It may reduce the need for other treatments and help the baby's gut work better.
This trial tests whether adding fluid into the womb (amnioinfusion) during labor can protect a baby's lungs and health after being exposed to thick meconium (baby's first poop). It may help reduce breathing problems and improve long-term outcomes.
This study tests whether giving breast milk through the rectum helps develop healthy gut bacteria in very premature babies who haven't passed their first stool within 48 hours of birth. Researchers believe this approach may improve digestion and overall health in these vulnerable infants.
This study tests whether giving caffeine to babies born with meconium aspiration syndrome, who still need oxygen at 10 to 14 days old, can help them breathe better and leave the hospital sooner.
This trial tests whether a saline-glycerin enema can help children with bowel leakage (fecal incontinence). It is designed for children aged 3 to 16 who have leakage due to certain conditions like corrected anal birth defects, Hirschsprung disease, or severe constipation.
This trial tests whether giving a single dose of the antibiotic Zinacef (cefuroxime) to women with meconium-stained amniotic fluid during labor can reduce infections. You may be eligible if you have a full-term, single baby and your water is stained with meconium.
Hear when a new Meconium Obstruction of Prematurity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.