Breast-milk enema to help premature babies pass first stool
Part of Digestive system clinical trials.
This study tests whether giving a small enema made from the mother's breast milk can help very premature babies pass their first stool (meconium) sooner. This may reduce the need for other interventions and support healthy digestion.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must be born between 23 and 28 weeks of pregnancy.
- Your baby must be born at or transferred within the first 24 hours to Atrium Health Wake Forest Baptist Hospital.
- Your baby must be at least 48 hours old and have not passed their first stool yet.
- You must be able to provide your own breast milk for the enema.
- You must give written permission for your baby to join the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a small amount of breast milk directly into the rectum can help premature babies develop healthy gut bacteria, especially if they haven't passed their first stool within 48 hours after birth.
This trial tests if giving a saline enema helps premature babies with meconium blockage pass stool, start feeding, and improve gut and brain health. It may reduce complications and help babies grow better.
This study tests whether placing small amounts of colostrum (the first breast milk) inside a premature baby's mouth can help them grow better. It is for babies born before 32 weeks and weighing less than 1500 grams.
This study looks at a stool test (fecal calprotectin) to see if it differs between preterm babies fed breast milk versus formula, and if it can help spot a serious gut condition called necrotizing enterocolitis (NEC). It may help find early signs of this condition.
This study compares different ways of feeding very premature babies to see which method helps prevent serious gut problems, reduces the risk of death, and supports brain growth. If your baby is born very early, this research may help find the safest feeding approach.
This study tests whether giving tiny amounts of human milk to the mouth early can help very preterm babies (born at 32 weeks or earlier) learn to feed better. It may reduce the time they need IV fluids or a feeding tube.
Hear when a new Breast Milk trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.