Chemotherapy after surgery for ampullary cancer
Treatments studied
Part of Cancer clinical trials.
This study tests whether giving chemotherapy after surgery (adjuvant chemotherapy) helps prevent ampullary cancer from coming back. It is for people who have had their ampullary cancer completely removed and are in reasonably good health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with ampullary cancer (a type of cancer near where the bile duct and pancreatic duct meet the small intestine).
- Your cancer was surgically removed entirely (with or without very small leftover cells under the microscope) and has not spread to other organs.
- You are generally healthy enough to carry out normal daily activities (WHO status 0 or 1).
- You are willing and able to start chemotherapy within 12 weeks after surgery.
- You have not had previous chemotherapy or radiation for this ampullary cancer, and have not had other cancers (except non-melanoma skin cancer) in the last 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares two types of chemotherapy to see which works better after surgery for ampullary cancer. One treatment is a stronger combination (FOLFIRINOX), and the other is a single drug (capecitabine or gemcitabine). It is for people whose cancer was completely removed by surgery and who have no spread to other organs.
This trial tests a specific chemotherapy after surgery for people with stage II or III bile duct, gallbladder, or ampullary cancer. It may help reduce the chance of cancer coming back.
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