Chemotherapy before surgery for advanced pancreatic cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests giving chemotherapy before any surgery to people with borderline resectable or locally advanced pancreatic cancer. The goal is to shrink the tumor, which may make surgery more successful and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with pancreatic cancer (adenocarcinoma), or a mixed tumor where adenocarcinoma is the main type.
- Your cancer is considered borderline resectable or locally advanced, meaning it is not easily removable by surgery at this time.
- You are 18 years or older.
- You are generally well enough to be up and about (ECOG score 0-1).
- Your blood counts and organ function (liver and kidneys) are within acceptable ranges.
- You have not had prior chemotherapy with gemcitabine, nab-paclitaxel, or FOLFIRINOX for pancreatic cancer.
- You have no other cancer in the last 3 years, except for certain non-melanoma skin cancers or treated low-risk prostate cancer.
- You are not pregnant or breastfeeding.
- You are willing to sign a consent form and follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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