Liver transplant with salt solution for colorectal liver metastases
Part of Cancer clinical trials.
This trial tests whether a liver transplant plus salt solution (a special preservation fluid) can help people with colorectal cancer that has spread to the liver but cannot be surgically removed. The goal is to see if this approach can stop cancer growth and improve survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Your colorectal tumor was surgically removed and its stage was T3N1 or less (and now at least 3 months since surgery), or if more advanced, at least 2 years since surgery.
- The liver tumors cannot be removed by surgery, and they are either in both lobes of the liver or only in the liver (with up to 1–3 removable spots in the lung).
- You have already received at least 6–8 weeks of first-line chemotherapy, and your liver tumors have not grown (they are stable or smaller).
- Your CEA level (a cancer marker) is 80 or less, or it has dropped by at least half with treatment.
- Your tumor does not have a BRAF mutation or microsatellite instability (MSI).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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