Liver transplant for colorectal cancer that has spread to the liver
Part of Cancer, Digestive system clinical trials.
This trial is testing a new approach for people whose colorectal cancer has spread to the liver and cannot be removed by surgery. The treatment involves a liver transplant, so it is for patients whose tumors are stable or improving after chemotherapy and have not spread beyond the liver (or have only a few removable lung spots). It aims to improve outcomes for patients with limited options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- Your colorectal cancer has spread only to the liver (or you have up to 3 removable spots in the lungs), and surgery to remove the liver tumors is not possible
- You have received at least 6 to 8 weeks of first-line chemotherapy and your liver tumors have stayed stable or shrunk (but not disappeared)
- The largest liver tumor is 5.5 cm or smaller
- Your tumor does not have a BRAF mutation or microsatellite instability (MSI)
- You are generally in good health (able to do light activities) and have no other serious illnesses that would make a transplant too risky
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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