Sex differences in small blood vessel problems of the heart
Part of Heart & circulation clinical trials.
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chest pain or discomfort (typical, atypical, or just shortness of breath).
- You have had a heart test (angiogram or CT scan) showing no major blockages (less than 50% narrowing).
- You do not have moderate or severe heart valve disease.
- You do not have congenital heart disease.
- Your kidneys work well enough (not on dialysis or with very low kidney function).
- You do not have asthma, COPD, or pulmonary hypertension.
- You are not currently taking anti-cancer drugs.
- You do not have autoimmune-related blood vessel inflammation.
- You do not have certain serious heart rhythm problems (like advanced heart block, very slow heart rate, or WPW syndrome).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people who have chest pain but don't have major blockages in their heart arteries. It aims to understand how the tiny blood vessels and artery spasms might be causing symptoms, using special heart tests.
This study looks at the tiny blood vessels in your heart (the microcirculation) that can cause chest pain even when the main arteries are open. It aims to better understand and treat this type of chest pain, called chronic coronary syndrome.
This study looks at how small blood vessels throughout your body work in women who have chest pain but no blocked arteries. Researchers want to understand if checking blood vessel function in your skin and other areas can help diagnose heart-related chest pain.
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
This study helps women with chest pain or heart symptoms who have normal-looking coronary arteries (the blood vessels that feed the heart). Researchers will perform specialized heart tests to understand why you have symptoms, then tailor treatment based on your specific condition.
Hear when a new Microvascular Angina trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.