Targeted medicines for chest pain without blocked arteries
Treatments studied
Part of Heart & circulation, Pain clinical trials.
This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chest pain (stable angina) and are being scheduled for tests in the heart catheterization lab.
- Angiogram shows no large blockages in the heart arteries, and a special pressure test (FFR) is greater than 0.80.
- You have at least one of: spasm in the large arteries or small vessels, reduced blood flow reserve, high microvascular resistance, or a heart muscle bridge with low pressure.
- You have not had a heart attack or unstable angina in the past week, and do not have a weakened heart muscle (cardiomyopathy).
- Your blood pressure is at least 95 mmHg (top number) and your resting heart rate is at least 55 beats per minute.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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