Choosing the best treatment for locally advanced breast cancer
Treatments studied
Part of Cancer clinical trials.
This study looks at different treatment plans for women with newly diagnosed, locally advanced breast cancer (stage IIIb-IIIc). It aims to find the most effective combination of surgery, chemotherapy, and radiotherapy. If you are a woman aged 18-70 with this diagnosis and your tumor can be surgically removed, this trial may be an option for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 18 and 70 years old.
- You have been newly diagnosed with locally advanced breast cancer (stage IIIb or IIIc).
- A doctor thinks your tumor can be removed with surgery, based on ultrasound showing it's not wrapped around a major vein in your armpit.
- You are willing to have surgery, chemotherapy, and radiation therapy as part of your treatment.
- You are willing to complete questionnaires about your quality of life and emotional well-being for the study.
- You have not had any previous breast cancer treatment (surgery, chemo, or radiation).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests adding a drug called adebrelimab to standard chemotherapy and possibly radiation, given before surgery for breast cancer that is HER2-negative and locally advanced. The goal is to see if this combination helps shrink tumors more effectively, potentially allowing for breast-conserving surgery.
This trial is testing whether giving radiation to nearby lymph nodes after surgery can help prevent breast cancer from coming back. It is for women with a specific type of breast cancer that has spread to a few lymph nodes but can be removed with surgery.
This trial studies whether adjusting radiation dose using how the tumor behaves can improve outcomes for people with locally advanced breast cancer that has spread to certain nearby lymph nodes. It may help deliver the right radiation intensity while avoiding unnecessary exposure.
This trial compares two treatments for locally advanced breast cancer: chemotherapy before surgery plus radiation, versus chemotherapy before surgery alone. The goal is to see which approach works better for this specific type of cancer.
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