Regional lymph node radiation after surgery for intermediate-risk breast cancer
Part of Cancer, Skin clinical trials.
This trial compares the benefits and risks of adding radiation therapy to the lymph nodes near the breast after surgery for people with breast cancer that has spread to a small number of lymph nodes. It may help prevent the cancer from coming back in those lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and are female.
- You had breast-conserving surgery or complete removal of the breast, plus removal of some underarm lymph nodes.
- No cancer cells at the edge of the removed tissue (negative margins).
- If you had surgery first: your tumor was small (pT1-2), had spread to 1-3 underarm lymph nodes (N1), and your risk score was low (0-2).
- If you had chemotherapy before surgery: you had a tumor that responded well (no cancer in the breast or lymph nodes at surgery) after at least 6 cycles of chemo.
- You do not have distant spread, cancer in the lymph nodes above the collarbone or under the breastbone, or previous radiation to the chest.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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