Freezing vs. medication for growing desmoid tumors
Treatments studied
Part of Cancer clinical trials.
This trial compares freezing the tumor (cryoablation) with standard medication for people with desmoid tumors that have grown or caused more symptoms. It aims to see which approach works better when the tumor is not in the belly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 13 years old.
- You must have a desmoid tumor that is not in your belly and has been confirmed by a biopsy.
- Your tumor must have grown or caused more symptoms after a period of watching and waiting.
- You must be able to have an MRI before the treatment starts.
- You must not have had any other cancer treatment for this tumor, and you must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether combining cryoablation (freezing the tumor) with nirogacestat (a targeted pill treatment) can better control desmoid tumors that are growing or causing symptoms. It may help shrink tumors and improve symptoms, especially when freezing alone is challenging.
This trial tests how safe and effective radiofrequency ablation (using heat to destroy tumor cells) is for people with desmoid tumors that are growing or causing symptoms.
This study tests a new medication for adults with desmoid tumors (rare, slow-growing tumors that form in connective tissue). You may qualify if your tumor has grown recently, causes pain, or has come back after previous treatment.
This study follows patients with desmoid tumors who are having a procedure called ablation, which uses heat or cold to destroy the tumor. The study asks patients about their symptoms and quality of life after the procedure to see how well it works.
This trial studies if freezing the main breast tumor (cryoablation) can help people with metastatic breast cancer who are already on treatment. It is for women whose cancer is stable or responding to treatment elsewhere in the body, but the breast tumor might still be growing.
This trial tests whether “cold therapy” (cryotherapy) can shrink or control desmoid tumors. It may help adults whose tumors are located in certain body areas where cryotherapy is considered safe.
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