Testing a New Drug for Desmoid Tumors
Part of Cancer clinical trials.
This study tests a new medication for adults with desmoid tumors (rare, slow-growing tumors that form in connective tissue). You may qualify if your tumor has grown recently, causes pain, or has come back after previous treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed desmoid tumor diagnosis (confirmed by biopsy or pathology report)
- Your tumor has grown by at least 20% in the past 12 months, new tumors have appeared, or you have desmoid-related pain not controlled by regular pain medication
- You either had at least one prior treatment (surgery, radiation, or systemic therapy) or your doctor believes you're suitable for this new drug without prior treatment
- You have at least one tumor lesion that can be measured on imaging scans
- Your overall health is good enough for treatment (ECOG score 0–2, meaning you can do most daily activities)
- You have adequate blood, liver, kidney, and clotting function (confirmed by blood tests)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether radiofrequency ablation (using heat to destroy the tumor) is safe and effective for treating desmoid tumors. If you have a growing or symptomatic desmoid, this treatment might help without major surgery.
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This trial compares freezing the tumor (cryoablation) with standard medication for people with desmoid tumors that have grown or caused more symptoms. It aims to see which approach works better when the tumor is not in the belly.
This Phase 2 study tests whether combining cryoablation (freezing the tumor) with nirogacestat (a targeted pill treatment) can better control desmoid tumors that are growing or causing symptoms. It may help shrink tumors and improve symptoms, especially when freezing alone is challenging.
This study tests a new drug called ES014 for people with advanced solid tumors that can't be removed or have spread. It's an early trial to see if ES014 is safe and helps fight certain cancers.
This trial tests a procedure called arterial chemoembolization (TACE) for people with symptomatic desmoid tumors that are growing and cannot be treated with surgery or cryoablation. The goal is to see if this targeted treatment can control the tumor and relieve symptoms.
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