Clin2
NCT06108492Possibly a fitRecruiting

A new bladder cancer drug given directly into the bladder

Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Part of Cancer, Kidney & urinary clinical trials.

This study tests a new drug, SHR-2005, given directly into the bladder through a catheter. It is for people with intermediate- or high-risk bladder cancer that hasn't spread into the muscle, and aims to see if it is safe and how well it works.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
170 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You have intermediate- or high-risk non-muscle invasive bladder cancer (confirmed by biopsy).
  • You are in good enough health to do daily activities (ECOG 0 or 1).
  • Your doctor expects you to live at least 2 more years.
  • You haven't had bladder surgery (like TURBT) in the last 2 weeks.
  • You haven't taken certain immunotherapy drugs (like OX40 or CD137 agonists) before.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06588179Not yet recruiting· Phase 1/Phase 2
New drug combination for high-risk bladder cancer not removable by scope

This trial tests two new drugs (SHR-1501 and SHR-2005) given directly into the bladder for people with high-risk bladder cancer that can't be fully removed with standard surgery and who aren't able to have their bladder removed. The goal is to see if this combination can control the cancer and avoid the need for bladder removal.

Shanghai, Shanghai Municipality
NCT07207824Recruiting· Phase 3
Study of a new drug for high-risk bladder cancer

This trial tests a combination of a drug (DV) and BCG immunotherapy for people with high-risk, early-stage bladder cancer that has not spread into the muscle. The cancer must show a specific protein called HER2 on its cells.

Shanghai, Shanghai Municipality
NCT06879145Recruiting· Phase 2/Phase 3
Study of SHR-A2102 and Adebrelimab for muscle-invasive bladder cancer

This trial tests a combination of two drugs, SHR-A2102 and Adebrelimab, for people with muscle-invasive bladder cancer that hasn't spread. The goal is to see if this treatment can help control the cancer.

Shanghai, Shanghai Municipality
NCT05410730Recruiting· Phase 1/Phase 2
Early bladder cancer study using new drugs and BCG

This trial tests whether a new bladder cancer drug (SHR-1501) works alone or combined with BCG, and compares options with another drug (SHR-1316), in people with high-risk non–muscle-invasive bladder cancer. It may help reduce cancer coming back and improve control of the disease.

Beijing, Beijing Municipality
NCT06639347Recruiting· Phase 1/Phase 2
Testing SHR-A2102 for advanced bladder cancer

This trial tests a new drug called SHR-A2102, which is a type of targeted therapy (an antibody-drug conjugate) for advanced urothelial carcinoma (bladder cancer). It may help if your cancer has not responded to standard treatments or if you are starting treatment for advanced disease.

Guangzhou, Guangdong
NCT07424287Recruiting· Phase 3
New drug plus BCG vs chemo for BCG-resistant bladder cancer

This trial tests a new combination treatment (SHR-1501 plus BCG) compared to standard chemotherapy for people with bladder cancer that hasn't responded to BCG. The goal is to see if this combination works better at controlling the cancer.

Beijing, Beijing Municipality

Hear when a new Intermediate and High-risk Non-muscle Invasive Bladder Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.