Adaptive quit-smoking treatment for early relapse

This study helps adults 21 and older who have tried to quit smoking with a stop-smoking medication. You may be able to join if you want to try quitting again or want to reduce harm from tobacco.

This study tests whether switching to a less harmful nicotine product (like a nicotine pouch or e-cigarette) can help people who are not ready to quit smoking reduce their health risks. You would be given a sample of a harm reduction product to try, and researchers will check how it affects your smoking habits.

This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.

This early-stage study tests ways to help adults who currently smoke daily start making progress toward quitting (or changing smoking habits) over the next 6 months. You may use nicotine replacement, and the study checks safety for people who can use it.

This study compares two ways to help people who are in treatment for substance use also quit or reduce smoking: using e-cigarettes or using standard nicotine replacement therapy (like patches or gum). If you're ready to make a change in your smoking, this could be a helpful option.

This study tests a new program to help young adults stop smoking. It uses medication and support to make quitting easier. If you join, you'll get help and maybe be part of a treatment group.