Adaptive quit-smoking treatment for early relapse

This study helps adults 21 and older who have tried to quit smoking with a stop-smoking medication. You may be able to join if you want to try quitting again or want to reduce harm from tobacco.

This study tests whether switching to a less harmful nicotine product (like a nicotine pouch or e-cigarette) can help people who are not ready to quit smoking reduce their health risks. You would be given a sample of a harm reduction product to try, and researchers will check how it affects your smoking habits.

This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.

This early-stage study tests ways to help adults who currently smoke daily start making progress toward quitting (or changing smoking habits) over the next 6 months. You may use nicotine replacement, and the study checks safety for people who can use it.

This study compares e-cigarettes to nicotine replacement therapy (like patches or gum) to help people who are in treatment for substance use disorder (like drugs or alcohol) quit or reduce smoking. It aims to find a safer way to cut back on cigarettes.

This study compares different nicotine replacement options to help people who smoke switch away from cigarettes. It may be a good fit if you smoke at least 5 cigarettes a day, aren't ready to quit in the next month, and are willing to stop using other stop-smoking aids.