Does nitrous oxide help with aggression?
Treatments studied
Part of Mental health clinical trials.
This study tests if a single dose of nitrous oxide (laughing gas) can reduce aggression in people with intermittent explosive disorder (IED). It compares their reactions to healthy volunteers without aggression issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 55 years old.
- You are generally physically healthy with no serious medical conditions.
- You can give informed consent to participate.
- For the aggression group: You have a current diagnosis of intermittent explosive disorder (IED) and aggression scores over 12 on a standard test.
- For the healthy group: You have no current or past psychiatric disorders and aggression scores under 12.
- You do not have a history of psychosis, bipolar disorder, intellectual disability, or current substance abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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