Can we skip dexamethasone before paclitaxel?
Treatments studied
Part of Cancer clinical trials.
This study tests whether it is safe to skip the steroid (dexamethasone) that is normally given before paclitaxel chemotherapy. If you are about to start paclitaxel for a solid tumor, this trial may help reduce side effects from premedication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have a solid tumor and your doctor plans to treat you with paclitaxel chemotherapy (any dose).
- You must be able to speak and understand Dutch.
- You have never received paclitaxel before.
- You are not allergic to paclitaxel, carboplatin, cetirizine, granisetron, ondansetron, or benzyl alcohol.
- You are not pregnant and are not already in another exercise study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how physical activity and body composition affect the side effects of paclitaxel, a chemotherapy drug, in women with stage II or III breast cancer. It aims to help doctors understand who might have more or fewer side effects during treatment.
This study looks at whether stopping routine allergy-prevention medicines before weekly paclitaxel chemotherapy affects your quality of life. If you qualify, you may be assigned to stop or continue these pre-medications and share how you feel.
This trial tests an oral form of the chemotherapy drug paclitaxel given before surgery for elderly patients with non-small cell lung cancer. The goal is to see if it helps shrink tumors and improve outcomes with fewer side effects than IV chemotherapy.
This trial gives weekly paclitaxel chemotherapy before breast surgery, then studies tumor “biomarkers” to see how well treatment is working. The goal is to improve how doctors predict which patients benefit and who may need different approaches.
This trial tests an oral form of a common chemo drug, paclitaxel, given before surgery for triple-negative breast cancer. It aims to find the best dose and see how well it shrinks tumors.
This trial tests a chemotherapy drug (paclitaxel) given directly into the belly for people whose appendix cancer has spread inside the belly and cannot be surgically removed. The goal is to see if this approach is safe and helps shrink tumors.
Hear when a new Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.