Early TIPS for variceal bleeding with portal vein clot
Part of Digestive system clinical trials.
This study tests whether placing a TIPS (a small tube in the liver to improve blood flow) early after a variceal bleed helps people with cirrhosis and a partial portal vein clot. It may reduce the risk of re-bleeding and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cirrhosis (liver scarring) diagnosed by your doctor.
- You are currently in the hospital for bleeding from enlarged veins in your esophagus or stomach.
- You have a blood clot in the main portal vein that blocks at least half of the vein.
- You have not had a TIPS or a surgical shunt in the past.
- You do not have liver cancer beyond certain limits or other cancers that limit your life to less than 6 months.
- You are not pregnant or breastfeeding, and you have no severe heart, lung, or kidney failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to prevent future bleeding from enlarged veins in the esophagus or stomach in people with liver cirrhosis. One method uses a small tube (called TIPS) to reduce pressure in the liver, and the other combines a banding procedure with medication. The goal is to see which approach works better.
This study tests a preventive procedure called TIPS, which places a small tube in the liver to lower blood pressure and prevent re-bleeding. It may help people with cirrhosis who have just had bleeding from stomach varices by reducing the chance of another bleed.
This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.
This study tests whether placing a small tube (called a TIPS) early in the liver can help people with cirrhosis who have their first episode of moderate to severe belly fluid buildup. The goal is to see if this early procedure improves outcomes compared to standard care.
This study tests a new way to guide a procedure called TIPS, which helps relieve pressure in the liver caused by fluid buildup or bleeding. The new guidance method may make the procedure safer or more precise.
This study looks at blood clotting in patients with cirrhosis who are getting a TIPS—a tube placed in the liver to help blood flow. The study aims to understand how the procedure affects bleeding and clotting, which could help make it safer for people with liver disease.
Hear when a new Portal Hypertension trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.