Clin2
NCT06129851Possibly a fitNot yet recruiting

Testing Relugolix with Radiation for High-Risk Prostate Cancer

Stage IIC Prostate Cancer AJCC v8Stage III Prostate Cancer AJCC v8Stage IV Prostate Cancer AJCC v8

Treatments studied

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new hormone pill called relugolix combined with radiation therapy for men with high-risk prostate cancer. The goal is to see if this combination improves treatment outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • Your prostate cancer must be considered high-risk or very high-risk by your doctor.
  • You must be able to receive radiation therapy (brachytherapy and/or external beam) plus hormone therapy (ADT).
  • You must not have had your prostate removed (prostatectomy).
  • You must not have had pelvic radiation therapy that would overlap with this treatment.
  • You must have adequate blood counts (for example, white blood cells, platelets) and liver function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07025369Recruiting· Phase 2
Hormone pill before PSMA scan for high-risk prostate cancer

This trial tests if giving a short-term hormone pill (relugolix) before a special PSMA PET/CT scan makes the scan clearer for men with high-risk prostate cancer. It may help doctors better see where the cancer is.

Scottsdale, Arizona
NCT06650579Recruiting· Phase 3
Heart safety study of relugolix vs leuprolide for prostate cancer

This trial compares two hormone therapy combinations for men with prostate cancer that hasn't spread. The goal is to see if a newer oral medication (Relugolix) plus abiraterone works better than the standard injectable therapy (Lupron) plus abiraterone, while also checking heart safety.

Atlanta, Georgia
NCT06330805Recruiting· Phase 2
Comparing heart effects of two hormone therapies for prostate cancer

This trial compares two hormone therapies, relugolix and leuprolide, to see which one is better for your heart health in men with prostate cancer. It's for men with a specific type of prostate cancer that is not yet advanced.

Columbus, Ohio
NCT06111781Recruiting· Phase 2
Hormone Therapy and Radiation for Intermediate Risk Prostate Cancer

This study tests whether a combination of short-term hormone therapy (relugolix) and focused radiation (SBRT) can treat a certain type of prostate cancer that is considered favorable but has a higher genetic risk. It aims to find a less intense treatment that still works well.

New Haven, Connecticut
NCT06499870Recruiting· Phase 2
Study of two drugs with radiation for high-risk prostate cancer

This trial tests whether combining two hormone therapy drugs, relugolix and enzalutamide, with radiation therapy can help treat very high-risk prostate cancer. The goal is to see if this combination is safe and effective for men whose cancer has a high chance of coming back.

Chicago, Illinois
NCT06130995Recruiting· Phase 1
Relugolix and enzalutamide for high-risk prostate cancer

This trial tests a combination of two oral drugs, relugolix and enzalutamide, in men with high-risk prostate cancer that hasn't spread to distant parts of the body. The goal is to see if this treatment can help control the cancer before or alongside local therapies like surgery or radiation.

Oklahoma City, Oklahoma

Hear when a new Stage IIC Prostate Cancer AJCC v8 trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.