Testing antibiotics before bladder removal surgery
Part of Cancer, Infections, Kidney & urinary clinical trials.
This trial tests whether giving preventive antibiotics before bladder removal surgery reduces infections. If you have muscle-invasive bladder cancer and are having your bladder removed, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have muscle-invasive bladder cancer and be scheduled for bladder removal surgery (radical cystectomy) with a urinary diversion (ileal conduit or neobladder).
- You must be 18 years or older.
- You cannot be currently taking antibiotics for an active infection.
- You must have adequate kidney function (GFR above 30 ml/min).
- You cannot be allergic to the antibiotic nitrofurantoin unless you can take an alternative like cephalexin, trimethoprim-sulfamethoxazole, or ciprofloxacin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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