Testing venetoclax with decitabine/cedazuridine for pediatric AML
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of two oral drugs (venetoclax and decitabine/cedazuridine) for children and teens whose acute myeloid leukemia (AML) has returned or not improved after prior treatment. The goal is to find a safe dose and see if the drugs can help shrink or control the leukemia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 2 and 18 years old.
- You have acute myeloid leukemia (AML) that has come back or not responded to treatment.
- You have at least 5% leukemia cells in your bone marrow or blood.
- You are able to swallow pills.
- Your liver and kidneys are working well enough (your doctor will check with blood tests).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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