Severe open fracture treatment: plate vs external fixator
Part of Infections, Injuries & trauma clinical trials.
This study compares two ways to fix severe open leg or arm fractures: a metal plate coated with antibiotics or a metal frame outside the body. It aims to see which method leads to fewer infections and better healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have a severe open fracture (Gustilo-Anderson type IIIA or IIIB) in a long bone like the thigh, shin, or upper arm.
- The fracture can be repaired with either a plate or a frame placed outside the skin.
- The wound can be closed during surgery, with a skin graft, or allowed to heal on its own.
- You do not have a brain injury, spinal cord injury, or severe burns.
- You are willing to follow up after treatment and do not have allergies to certain antibiotics (ceftriaxone or sulbactam).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
This study compares two ways to surgically treat a specific type of wrist fracture (where the break extends into the joint). Researchers will compare a metal plate attached to the inside of the wrist versus an external fixator (a metal frame attached to the outside) to see which helps patients recover better.
This Phase 3 study compares two ways to help heal a severe open tibia (shin bone) fracture and prevent complications like infection. If you qualify, you may receive antibiotic beads or a negative pressure wound therapy dressing after urgent wound cleaning.
This study compares two surgical techniques for fixing a break in the middle of the upper arm bone. It aims to find which approach leads to better healing and recovery for patients.
This trial tests a new type of metal plate designed to fix a broken hip (femoral neck fracture) with sliding compression. The goal is to see if this plate helps the bone heal better and faster.
Hear when a new Fracture Related Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.