Clin2
NCT06195982Possibly a fitCompleted

Ketone supplement for heart failure with reduced pumping ability

Heart Failure With Reduced Ejection Fraction

Part of Heart & circulation, Hormones & metabolism clinical trials.

This trial tests whether a ketone supplement can improve heart function and exercise ability in people with heart failure and a reduced ejection fraction. It may help you feel better during daily activities.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
25 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been on stable heart medications for at least 2 weeks.
  • You have heart failure with a reduced pumping ability (ejection fraction of 45% or less) and have symptoms like shortness of breath or fatigue during activity (NYHA class II or III).
  • You have not been on a keto diet in the last week.
  • You do not have type 1 diabetes.
  • You do not have serious liver disease or heavy alcohol use.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06229678Recruiting· Early Phase 1
Ketones and diabetes drug for heart failure with weak pump

This clinical trial looks at whether adding a special diet supplement (ketones) to an SGLT2 inhibitor diabetes drug improves heart function and symptoms in people who have both type 2 diabetes and heart failure with a weakened heart muscle.

San Antonio, Texas
NCT06937320Enrolling by invitation· Phase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)

This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.

Durham, North Carolina
NCT06653725Recruiting· Phase 2
Ketone supplement study for hospitalized heart failure patients

This trial tests if a ketone supplement can help people hospitalized for acute heart failure. The supplement is given orally and aims to support the heart and energy levels during recovery.

Aalborg
NCT07434466Not yet recruiting
Ketone drink for acute heart failure recovery

This trial tests a special ketone drink to see if it can help people recently hospitalized with acute heart failure feel better and recover faster. It measures how the drink affects the heart and body during the early days in the hospital.

Edmonton, Alberta
NCT06108076Recruiting· Early Phase 1
Oral ketones for heart failure and diabetes

This study tests whether taking a special oral ketone supplement can help people with both heart failure and diabetes. It looks at both short-term and long-term effects on heart function and blood sugar control.

San Antonio, Texas
NCT07166965Enrolling by invitation
Supplement for Heart Failure: Ketones and Hawthorn

This trial tests whether adding a supplement containing ketones and hawthorn extract can help people with heart failure feel better and improve their heart function. You will take the supplement daily and have imaging scans and exercise tests to monitor your progress.

Philadelphia, Pennsylvania

Hear when a new Heart Failure With Reduced Ejection Fraction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.