Comparing ticagrelor and cilostazol for large-vessel stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial compares two antiplatelet drugs (ticagrelor and cilostazol) to see which is better at preventing another stroke in people who have had a large-vessel ischemic stroke. Both drugs help keep blood clots from forming, and the study aims to find the safest and most effective option for patients who cannot receive clot-busting medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- This is your first stroke caused by a large blood clot in a major artery (or you've had a TIA, which is a mini-stroke).
- You started taking an antiplatelet medication (like aspirin, clopidogrel, or other) within 24 hours of your stroke.
- You are not eligible for clot-busting medication (tPA).
- You do not have active bleeding, a history of bleeding problems, recent major surgery, or other serious conditions like cancer or recent heart attack.
- Your blood pressure, blood sugar, and platelet count are within certain safe ranges at the time of screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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